Description
Recombinant form of Human Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5 or CEA), which is produced under serum‐free conditions in HEK 293 cells. The expression construct contains residues 1 to 677 of human CEA and with a 25 amino acid C-terminal truncation (Δ678–702) compared to full-length CEA, which contains 702 amino acids. The amino acid sequence is identical to residues 1 to 677 of GenBank entry AAA62835.1. With respect to reviewed UniProtKB entry P06731, this construct contains five sequence deviations: N359I, N360I, Q361R, F641L, T646Q. The recombinant protein is produced under serum‐free conditions in optimized HEK293-cell system and purified through using ion exchange chromatography and Size Exclusion Chromatography